EDTA Chelation. Elevated.

Detoxamin is scientifically proven chelation therapy designed to help your body clear the burden it can’t remove on its own — so you can feel lighter, sharper, and more like yourself again.

Heavy Metal Exposures Are An Established Global Health Concern

Today we have to cope with an ever-increasing load of toxins in this industrial 21st century. They include air pollutants and heavy metal contaminants. However, nearly 100 years of evidence shows that EDTA chelation can effectively address our modern heavy metal issues. Free radicals produced in the cell itself comprise only a fraction of the "oxidative stress" load with which the cell must cope. Other sources of free radicals include air pollutants and exposure to heavy metal contaminants.

Detoxamin’s EDTA formula is grounded in rigorous scientific research and proven effective through clinical trials.

Backed by a robust scientific foundation and confirmed by clinical studies, Detoxamin delivers reliable, evidence-based results.

Frequent Questions

More Sustained Chelation

Intravenous (IV) chelation therapy delivers ethylenediaminetetraacetic acid (EDTA) directly into the bloodstream, resulting in rapid systemic distribution and elimination within approximately three hours. Independent laboratory analyses have demonstrated that calcium disodium EDTA (CaNa₂EDTA) administered via Detoxamin® suppositories remains bioavailable for at least eight hours, providing a slower, more sustained chelation.

Higher Tissue Mobilisation

Detoxamin® facilitates gradual absorption of CaNa₂EDTA through the colonic mucosa, producing prolonged and stable plasma EDTA concentrations. This extended pharmacokinetic profile enhances the compound’s ability to mobilize and chelate toxic metals from tissue reservoirs rather than acting solely within the circulatory system. The biphasic absorption pattern observed with Detoxamin® reflects alternating increases and decreases in blood EDTA levels as the compound circulates and binds to metal ions.

Gentle Slow Acting

Detoxamin provides continual, slow-acting detoxification—even during sleep—reducing accelerated aging from lipid peroxidation while promoting vitality, energy, and well-being. Its gentle, slow absorption continues to remove metals after initial provocation, supporting healthy brain, neurological, cardiovascular, and bone function, maintaining metabolism, decreasing free-radical damage, and improving cognitive clarity.

Significant Blood & Tissue Levels

The slow and consistent movement of EDTA via Detoxamin's patented formula is scientifically proven to provide significant blood and tissue levels longer to do its chelating work, without a high dose EDTA IV drip given over many hours. Halts the oxidative damage we all experience,

Continuous, Safer EDTA Delivery

Detoxamin introduces EDTA through the body at a much slower rate, alleviating an undue burden on the liver and kidneys. It delivers a continuous lower dose concentration of EDTA for over longer periods of time compared to IV so the EDTA can bind to metals more efficiently and effectively.

glutathione

Targeted Heavy Metal Chelation

Detoxamin is proven to deliver higher amounts of EDTA in prostate tissue compared to IV, having far-reaching implications for more complete distribution of EDTA into interstitial and intracellular spaces, this leads to more efficient chelation of compartmentalised heavy metals.

  • The body has not learned how to dispose of heavy metals, even in very low concentrations, and tends to store them.
  • Metals are stored in lymphatic and circulatory systems, vital organs such as the brain and the liver, and also in fatty tissues.
  • EDTA removes heavy metals from the body by binding to them. Because EDTA has an affinity to toxic heavy particles, it attracts and binds to heavy metals.
  • The toxic ion and the amino acid connect, the body regards the EDTA as a foreign substance, sends kidney for elimination. Both the EDTA and the heavy metals get a free ride into the toilet.

The Preferred Choice

EDTA and glutathione are essential for supporting your body’s cellular, mitochondrial, and cardiovascular health, with scientifically proven benefits that extend to overall wellness and longevity. Yet, traditional IV therapy can be costly, time-consuming, and uncomfortable for many people. But now there’s Detoxamin—a groundbreaking, accessible solution that unlocks these advanced health benefits without the barriers of invasive treatments.

Supports Cellular Renewal

Promotes detoxification and protects cells from oxidative stress for improved vitality.

Enhances Cardiovascular Health

Detoxamin helps remove heavy metals and supports healthy blood flow and circulation.

Boosts Longevity and Energy

Strengthens mitochondrial function to increase energy, resilience, and overall wellness.

Proven Clinical Benefits

  • Continual slow acting gentle and elegant detoxification during sleep
  • Diminishes the accelerated aging process due to lipid peroxidation
  • Promotes feelings of vitality, increased energy & well-being
  • Continues to remove metals after initial provocation
  • Lessens shock to system through slow-absorption
  • Supports healthy brain and neurological function
  • Simple, convenient and easy to self-administer
  • Well tolerated during hemorrhoidal conditions
  • A significant adjunct to replace IV therapy
  • Helps maintain healthy body metabolism
  • Well tolerated by adults and children
  • Clears toxic metal buildup in tissues
  • Supports cardiovascular health
  • Decreases free-radical damage
  • Gentle, non-invasive and safe
  • Improves cognitive function
  • Facilitates toxic elimination
  • Increases mental clarity

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Health-aware professionals choose Detoxamin.

Intravenous chelation therapy administers EDTA directly into the bloodstream; therefore the EDTA is introduced very quickly into the body causing the body to get rid of the EDTA in 3 hours. Verified by independent laboratory studies, the Ca-EDTA contained in Detoxamin stays in the body at least 8 hours, allowing for a gentler and more elegant chelation experience.

Detoxamin introduces Ca-EDTA through the colon wall slowly allowing for a much slower moving EDTA and longer lasting EDTA blood levels. This allows for more time so that the EDTA can absorb and chelate the toxic metals where they are stored, not just in the bloodstream. Detoxamin’s long lasting EDTA is actually bi-phasic, where the EDTA blood levels fluctuate up and down over time as the EDTA makes its way through the body picking up toxic metals.

One major difference is Detoxamin has a higher EDTA soft tissue absorption, effectively “tickling” out the heavy metals where the body is storing and tucking them away. The slow and consistent movement of EDTA via Detoxamin’s patented formula is scientifically proven to provide significant blood and tissue levels to chelate toxic metals without a high dose EDTA IV drip over many hours.

Take charge — unlock your best health today

Productive Form Of Chelation

The lower and middle hemorrhoidal veins bypass the liver-and do not undergo first pass metabolism. This means that the EDTA in Detoxamin goes directly to the organs of your body without being filtered through the liver first. Because of this, the EDTA contained in Detoxamin is very productive.

High Systemic EDTA Absorption

Detoxamin’s mechanism allows the EDTA to absorb through the colon wall while you sleep. Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system, so absorption through the rectal wall carries EDTA in Detoxamin to the portal vein. The lower and middle hemorrhoidal veins bypass the liver, and do not undergo first pass metabolism.

Systemic EDTA Circulation

Detoxamin also introduces EDTA directly into the systemic circulation, efficiently bypassing the portal circulation and the liver metabolism on the first pass. Rectal absorption may also occur through the lymphatic system and, in some cases, largely through the blood via the vena cava.

Solid Scientific Framework

The efficacy of Detoxamin’s formula is based on solid scientific framework and verified through clinical trials, and offers many advantages both over the expensive intravenous method of EDTA chelation. Eliminates the the use of needles via the intravenous method, and the risk of other communicable blood-borne diseases.

Clinically Proven

Reclaim your health with science-backed Detoxamin

Detoxamin allows absorption into the Lymphatic System unlike any other chelators known. The most powerful free radical fighter you have is your lymphatic system. Your lymphatic system holds 80% of your body’s anti-oxidant capacity and is your body’s second circulatory system. Wherever your blood stream goes, the lymphatic system is right next to it. In fact, the lymphatic stream parallels the blood stream.

Detoxamin detoxification works on specific FOCI, (focal areas of interference or disturbance within the body.) If there is a localized problem someone is having, there is often lymphatic stasis involved with concurrent mineral imbalance at the interstitial / cell level.

Detoxamin with EDTA brings benefits to every blood vessel in the body, from the largest arteries to the tiniest capillaries,. In many cases, the smallest blood vessels are the most severely damaged. The benefits of chelation occur from the top of the head to the bottom of the feet, not just in a few large arteries.

Your Gentle, At-Home Alternative to IV Chelation

Controls Free Radicals

These renegade molecules oxidize or burn holes in the cell membranes and this action can lead to cell death. If only we would be as concerned about free radicals and their impact on the membranes of our cells as we are about putting on sunscreen to protect our skin! The action is similar and it's just as important to our health.

Cellular Level

Binds to toxic metals at the cellular level, thereby reducing free radicals, reversing cross-linking, improves membrane fluidity and improves cell signalling. Oxidative damage causes a net stress on the normal body functions. It also appears to contribute to the general decline in the optimum body functions, that is commonly believed to occur as a result of “aging process”.

Binds with Mercury

The EDTA contained in Detoxamin has an extra chemical bond compared to the older Disodium EDTA. This gives Detoxamin EDTA an affinity for MERCURY. Mercury is also excreted from the body through the feces, because Detoxamin utilizes the colon wall for EDTA assimilation, it is a powerful Mercury chelator.

Endothelial Function

Supports normal endothelial function, which is vital to a healthy cardiovascular system. (The endothelium is a saran-wrap-like lining inside the 7,000 miles of blood vessels in your body.) Heavy metals prevent the optimal production of nitric oxide, which is crucial to cardiovascular and overall health.

Safer than IV

Detoxamin's EDTA travels through the body at a much slower rate, alleviating undue burden on the liver and kidneys. Taken at night, right before bed allows less metabolic competition as the body is at rest. It introduces less dosage but it is done more frequently. This is just like taking vitamins providing better EDTA assimilation.

Benefits Every Cell

Detoxamin with EDTA doesn’t enter into the cells, rather it circulates outside the cells and cleanses these areas and blood vessels exposed to stress and toxins. Detoxamin's EDTA targets metals and toxins from the “wrong places” (blood vessels and joints) and stops free radical damage by scavenging certain minerals that are promoting the free radical process.

What Are You Doing To Address Cellular Oxidative Stress in Your Patients?

The first step in intelligent medical intervention for the 21st century.

A senior male doctor standing with a fmeale junior doctor

"Metal Toxicity: A Growing Health Challenge Linked to Environmental Oxidative Toxins."

A plethora of published biomedical studies clearly indicate the insidious toxicity on non-physiological metals, and the specific mechanisms and dysregulary effects of the metals have been well elucidated. Environmental exposure to heavy metals in our society is becoming a more clinically significant medical condition on a daily basis. If unrecognised or inappropriate treated, heavy metal toxicity, especially lead, arsenic, mercury, nickel and others and is affecting people worldwide.

Concern for your patients must be more widespread and long-term observation of and protection from these dangers. The detection, reduction, and elimination of toxic metals is a specialized field of medicine that is becoming more and more recognized as essential.

The sheer numbers of people who would benefit from chelation therapy preclude effective case management in established IV therapy. Clearly, a simply and effective more convenient therapy such as Detoxamin EDTA suppositories are needed.

References

  • Benefits of EDTA Chelation Therapy in Arteriosclerosis a Retrospective Study of 470 Patients by C. Hancke, MD, and K. Flytlie, MD
  • A Pilot Double Blind Study of Sodium Magnesium EDTA in Peripherral Vascular Disease by Efrain Olszewer, MD, Fuad Calil Sabbag, MD, and James P. Carter, MD, DrPH New Orleans, Louisiana
  • EDTA Chelation Therapy Efficacy in Arteriosclerotic Heart Disease by H. Richard Casdorph, MD, PhD
  • EDTA Chelation Therapy III Treatment of Peripheral Arterial Occlusion an Alternative to Amputation by H. Richard Casdorph, MD, PhD and Charles H. Farr, MD, PhD
  • EDTA Chelation Therapy in Chronic Degenerative Disease by EFRAIN OLSZEWER and JAMES P. CARTER
  • The Correlation Between EDTA Chelation Therapy and Improvement in Cardiovascular Function A Meta Analysis by L. Terry Chappell, MD, and John P. Stahl, PhD
  • 6 Children with Lead Poisoning by John A, Friedman, MD, Howard L. Weinberger, MD
  • A Nonsurgical Approach to Obstructive Carotid Stenosis Using EDTA Chelation by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and R.K. Barber, BS, ACSM, ETT
  • Absorbtion of Drugs from the Rat Colon by Lewis S. Schanker by Lewis S. Schanker
  • An Observation of the Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation onBlood Platelet Volume a Brief by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and R.K. Barber, BS, ACSM, ETT
  • An Oculocerebrovasculometric Analysis of the Improvement in Arterial Stenosis Following EDTA Chelation Therapy by E.W. McDonagh, DO, FACGP, C.J. Rudolph, DO, PhD, E. Cheraskin, MD, DMD
  • Beneficial Effects of Zinc Supplementation During Chelation Treatment of Lead Intoxication in Rats by S.J.S. Flora and S.K. Tandon
  • Carotid Restenosis a Case for EDTA Chelation by H. Joseph Holliday, MD, FACA, RVT
  • Chelation Therapy a Survey of Treatment Outcomes and Selected SocioMedical Factors by Wesley J. Adams, PhD, and Charles T. McGee, MD
  • Chelation Therapy of Occlusive Arteriosclerosis in Diabetic Patients by Carlos P. Lamar, MD, F.I.C.A.
  • Chronic Diseases A Practical Method for the Reduction of Plasma Cholesterol in Man by Henry A. Schroeder, M.D.
  • Current Status of EDTA Chelation Therapy in Occlusive Arterial Disease , MD by Elmer M. Cranton, MD, James P. Frackelton
  • Demographic Data and Treatment of Small Companion Animals With Lead Poisoning 347 Cases 1977 to 1986 by Rhea V. Morgan, DVM; Laurie K. Pearce, DVM; Frances M. Moore, DVM; Thomas Rossi, DVM, MS
  • Disappearance of Immune Deposits with EDTA Chelation Therapy in a Case of IgA Nephropathy by Ja-Liang Lin, MD
  • Disintergration of Retroviruses by Chelating Agents by V. Wunderlich and G. Sydow
  • EDTA Chelation Treatment for Vascular Disease A Meta Analysis Using Unpublished Data by L. Terry Chappell, MD, John P. Stahl, PhD, and Ronald Evans, MA
  • Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation Chronic Lung Disorders A Study of FVC and FEV by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and Rhonda.K. Barber, BS, ACSM, ETT
  • Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation on Carotid Circulation Case Report by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP
  • Effect of EDTA Chelation Therrapy Plus Multivitamintrace Mineral Supplementation Upon Vascular Dynamics Ankle Brachial Doppler Systolic Blood Pressure Ratio by E.W. McDonagh, DO, C.J. Rudolph, DO, E Cheaskin, MD, DMD
  • Lead Nephropathy Gout and Hypertension by Vicihi Batuman, MD, FACP
  • Lead Toxicity Chelation Therapy New Findings by R. Gooneratne and A. Olkowski
  • Magnetic Resonance Imaging Evidence of a Reduction in Disc Herniation Using a Combination of EDTA Chelation and Joint Reconstructive Therapy by C.J. Rudolph, DO, PhD, FACAM, E.W. McDonagh, DO, ACGP, FACAM
  • Mineral Excretion Associated with EDTA Chelation Therapy by Hugh D. Riordan, M.D., Emanuel Cheraskin, M.D., D.M.D., and Marvin Dirks, B.D., M.A.
  • Visual Field Evidence of Macular Degeneration Reversal Using a Combination of EDTA Chelation and Multiple Vitamin and Trace Mineral Therapy by C.J. Rudolph, DO, PhD, FACAM, R.T. Samuels, OD, and E.W. McDonagh, DO, ACGP, FACAM
  • Potential Uses of Chelation Methods in the Treatment of Cardiovascular Diseases by J. Roderick Kitchell, Lawrence E. Meltzer and Marvin J. Seven
  • Reduction of Elevated Plasma Lipid Levels in Artherosclerosis following EDTA Therapy by J. H. Olwin and J. L. Koppel
  • Safety Evalutation Studies of Calcium EDTA by Bernard L. Oser, Mona Oser and Howard C. Spencer
  • The “Clinical Change“ in Patients Treated with EDTA Chelation Plus Multivitamin/Trace Mineral Supplementation by Edward W. McDonagh, D.O., Charles J. Rudolph, Ph.D., D.O., and Emanuel Cheaskin, M.D., D.M.D.
  • The Correlation Between EDTA Chelation Therapy and Improvement in Cardiovascular Function: A Meta-Analysis by L. Terry Chappell, MD, and John P. Stahl, PhD
  • The Current Status of EDTA Chelation Therapy by Elmer M. Cranton, MD
  • The Effect of Calcium Chelation on Cardiac Arrythmias and Conduction Disturbances by Sidney Jick, M.D. and Robert Karsh, M.D.
  • The Effect of EDTA Chelation Therapy Plus Supportive Multivitamin Trace Mineral Supplementation Upon Renal Function: A Study in Blood Urea Nitrogen (BUN) by E.W. McDonagh, DO, C.J. Rudolph, DO, PhD, E. Cheraskin, MD, DMD
  • The Effect of EDTA Chelation Therapy Plus Supportive Multivitamin Trace Mineral Supplementation Upon Renal Function: A Study in Serum Creatinine by EW McDonagh, DO, CJ Rudolph, PhD, DO, E Cheraskin, MD, DMD
  • The Effects of Thiamin on Lead Metabolism: Whole Body Retention of Lead-203 by Jin Suk Kim, Donald L. Hamilton, Barry R, Blakley, and Colin G. Rousseaux
  • The Efficacy of Chelation Therapy and Factors Influencing Mortality in Lead Intoxicated Petrol Sniffers by C. B. Burns PhD, B. Currie
  • Treatment of Occlusive Vascular Disease with Disodium Ethylene Diamine Tetraacetic Acid (EDTA) by Norman E. Clarke, Sr. M.D., Norman E. Clarke Jr. M.D. and Robert E. Mosher, PhD
  • Proof of EDTA’s Permeability by way of the Colon by M. Ella, R Behrens, C Northrop, P Wraight and G. Neale Dunn Clinical Nutrition Centre and New Addenbrooke’s Hospital, Cambridge, U.K.

Tips for optimizing performance

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